Lecture: Introduction Pharmacokinetics

This lecture introduces the fundamentals of pharmacokinetics, covering the ADME processes, key PK parameters, and their relevance for individualized therapy and drug disposition.

Learning Objectives

The main learning objectives are

• 🎯 Define pharmacokinetics (PK) and differentiate it from pharmacodynamics (PD).
• 🎯 Explain the four ADME processes (Absorption, Distribution, Metabolism, Excretion).
• 🎯 Understand the importance of PK in therapy optimization and personalized medicine.
• 🎯 Identify key PK parameters (e.g., AUC, half-life, clearance, volume of distribution).
• 🎯 Recognize factors influencing drug disposition (e.g., bodyweight, pharmacogenomics, organ function).

Lecture

Download: L01_Koenig_MB19_Pharmacokinetics.pdf