Lecture: Absorption and Dosing

This lecture explores the principles of drug absorption and dosing, including routes of administration, bioavailability, absorption models, and how dosing strategies affect plasma concentrations and therapeutic outcomes.

Learning Objectives

The main learning objectives are

• 🎯 Understand the principles of drug absorption and factors that influence it.
• 🎯 Describe common routes of administration and their impact on absorption.
• 🎯 Explain the concept of bioavailability and first-pass metabolism.
• 🎯 Explore models of oral absorption (e.g., first-order, zero-order, lag time).
• 🎯 Understand the relationship between dosing, absorption rate, and plasma concentration.
• 🎯 Compare single vs. multiple dosing and their effects on drug levels.
• 🎯 Apply absorption and dosing concepts to optimize drug therapy.

Lecture

Download: L04_Koenig_MB19_Absorption.Dosing.pdf